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The elusive nature and diagnostics of misfolded Aβ oligomers

Amyloid-beta (Aβ) peptide oligomers are believed to be the causative agents of Alzheimer's disease (AD). Though post-mortem examination shows that insoluble fibrils are deposited in the brains of AD patients in the form of intracellular (tangles) and extracellular (plaques) deposits, it has bee...

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Detalles Bibliográficos
Autores principales: Cerasoli, Eleonora, Ryadnov, Maxim G., Austen, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365737/
https://www.ncbi.nlm.nih.gov/pubmed/25853119
http://dx.doi.org/10.3389/fchem.2015.00017