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Comorbidities of patients in tiotropium clinical trials: comparison with observational studies of patients with chronic obstructive pulmonary disease

BACKGROUND: There is an ongoing debate on whether patients with chronic obstructive pulmonary disease (COPD) seen in real-life clinical settings are represented in randomized controlled trials (RCTs) of COPD. It is thought that the stringent inclusion and exclusion criteria of RCTs may prevent the p...

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Detalles Bibliográficos
Autores principales: Miravitlles, Marc, Price, David, Rabe, Klaus F, Schmidt, Hendrik, Metzdorf, Norbert, Celli, Bartolome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365745/
https://www.ncbi.nlm.nih.gov/pubmed/25834416
http://dx.doi.org/10.2147/COPD.S71913