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Comorbidities of patients in tiotropium clinical trials: comparison with observational studies of patients with chronic obstructive pulmonary disease
BACKGROUND: There is an ongoing debate on whether patients with chronic obstructive pulmonary disease (COPD) seen in real-life clinical settings are represented in randomized controlled trials (RCTs) of COPD. It is thought that the stringent inclusion and exclusion criteria of RCTs may prevent the p...
Autores principales: | Miravitlles, Marc, Price, David, Rabe, Klaus F, Schmidt, Hendrik, Metzdorf, Norbert, Celli, Bartolome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365745/ https://www.ncbi.nlm.nih.gov/pubmed/25834416 http://dx.doi.org/10.2147/COPD.S71913 |
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