Plumbagin induces G(2)/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone; PLB), a naturally occurring naphthoquinone isolated from the roots of Plumbaginaceae plants, has been reported to possess anticancer activities in both in vitro and in vivo studies, but the effect of PLB on tongue squamous cell carcinoma (TSCC) is no...

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Detalles Bibliográficos
Autores principales: Pan, Shu-Ting, Qin, Yiru, Zhou, Zhi-Wei, He, Zhi-Xu, Zhang, Xueji, Yang, Tianxin, Yang, Yin-Xue, Wang, Dong, Qiu, Jia-Xuan, Zhou, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365758/
https://www.ncbi.nlm.nih.gov/pubmed/25834400
http://dx.doi.org/10.2147/DDDT.S76057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365758/
https://www.ncbi.nlm.nih.gov/pubmed/25834400
http://dx.doi.org/10.2147/DDDT.S76057

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