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Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis – an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks

BACKGROUND: There are several guidelines addressing the issues around the use of NSAIDs. However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk of COX-2 selective and non-selective compounds nor the interaction at both the GI and cardiovascular (CV) level of eithe...

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Detalles Bibliográficos
Autores principales: Scarpignato, Carmelo, Lanas, Angel, Blandizzi, Corrado, Lems, Willem F, Hermann, Matthias, Hunt, Richard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365808/
https://www.ncbi.nlm.nih.gov/pubmed/25857826
http://dx.doi.org/10.1186/s12916-015-0285-8