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Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells

BACKGROUND: Malignant glioma is one of the most devastating tumors in adults with poor patient prognosis. Notably, glioma often exhibits resistance to conventional chemotherapeutic approaches, complicating patient treatments. However, the molecular mediators involved in tumor chemoresistance remain...

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Detalles Bibliográficos
Autores principales: Sukumari-Ramesh, Sangeetha, Prasad, Niyathi, Alleyne, Cargill H, Vender, John R, Dhandapani, Krishnan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365816/
https://www.ncbi.nlm.nih.gov/pubmed/25851054
http://dx.doi.org/10.1186/s12885-015-1134-z