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Complete restoration of multiple dystrophin isoforms in genetically corrected Duchenne muscular dystrophy patient–derived cardiomyocytes

Duchenne muscular dystrophy (DMD)–associated cardiac diseases are emerging as a major cause of morbidity and mortality in DMD patients, and many therapies for treatment of skeletal muscle failed to improve cardiac function. The reprogramming of patients’ somatic cells into pluripotent stem cells, co...

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Detalles Bibliográficos
Autores principales: Zatti, Susi, Martewicz, Sebastian, Serena, Elena, Uno, Narumi, Giobbe, Giovanni, Kazuki, Yasuhiro, Oshimura, Mitsuo, Elvassore, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365821/
https://www.ncbi.nlm.nih.gov/pubmed/26015941
http://dx.doi.org/10.1038/mtm.2013.1