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Aurintricarboxylic acid increases yield of HSV-1 vectors

Production of large quantities of viral vectors is crucial for the success of gene therapy in the clinic. There is a need for higher titers of herpes simplex virus-1 (HSV-1) vectors both for therapeutic use as well as in the manufacturing of clinical grade adeno-associated virus (AAV) vectors. HSV-1...

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Detalles Bibliográficos
Autores principales: Pechan, Peter, Ardinger, Jeffery, Ketavarapu, Jyothi, Rubin, Hillard, Wadsworth, Samuel C, Scaria, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365865/
https://www.ncbi.nlm.nih.gov/pubmed/26015945
http://dx.doi.org/10.1038/mtm.2013.6