P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment

Duchenne muscular dystrophy (DMD) is a lethal inherited muscle disorder. Pathological characteristics of DMD skeletal muscles include, among others, abnormal Ca(2+) homeostasis and cell signalling. Here, in the mdx mouse model of DMD, we demonstrate significant P2X7 receptor abnormalities in isolate...

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Detalles Bibliográficos
Autores principales: Young, Christopher N J, Brutkowski, Wojciech, Lien, Chun-Fu, Arkle, Stephen, Lochmüller, Hanns, Zabłocki, Krzysztof, Górecki, Dariusz C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365874/
https://www.ncbi.nlm.nih.gov/pubmed/21794079
http://dx.doi.org/10.1111/j.1582-4934.2011.01397.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365874/
https://www.ncbi.nlm.nih.gov/pubmed/21794079
http://dx.doi.org/10.1111/j.1582-4934.2011.01397.x

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