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Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer’s disease

Accumulation of amyloid β (Aβ) is a major hallmark in Alzheimer’s disease (AD). Bone marrow derived monocytic cells (BMM) have been shown to reduce Aβ burden in mouse models of AD, alleviating the AD pathology. BMM have been shown to be more efficient phagocytes in AD than the endogenous brain micro...

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Detalles Bibliográficos
Autores principales: Magga, Johanna, Savchenko, Ekaterina, Malm, Tarja, Rolova, Taisia, Pollari, Eveliina, Valonen, Piia, Lehtonen, Šárka, Jantunen, Esa, Aarnio, Jussi, Lehenkari, Petri, Koistinaho, Milla, Muona, Anu, Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365885/
https://www.ncbi.nlm.nih.gov/pubmed/21777378
http://dx.doi.org/10.1111/j.1582-4934.2011.01390.x