Cargando…

Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer’s disease

Accumulation of amyloid β (Aβ) is a major hallmark in Alzheimer’s disease (AD). Bone marrow derived monocytic cells (BMM) have been shown to reduce Aβ burden in mouse models of AD, alleviating the AD pathology. BMM have been shown to be more efficient phagocytes in AD than the endogenous brain micro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magga, Johanna, Savchenko, Ekaterina, Malm, Tarja, Rolova, Taisia, Pollari, Eveliina, Valonen, Piia, Lehtonen, Šárka, Jantunen, Esa, Aarnio, Jussi, Lehenkari, Petri, Koistinaho, Milla, Muona, Anu, Koistinaho, Jari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365885/ https://www.ncbi.nlm.nih.gov/pubmed/21777378 http://dx.doi.org/10.1111/j.1582-4934.2011.01390.x

Ejemplares similares

ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
por: Lemarchant, Sighild, et al.
Publicado: (2016)

Erratum to: ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
por: Lemarchant, Sighild, et al.
Publicado: (2016)

Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta Clearance
por: Malm, Tarja, et al.
Publicado: (2012)

Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis
por: Korhonen, Paula, et al.
Publicado: (2019)

Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis
por: Pollari, Eveliina, et al.
Publicado: (2011)

Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele
por: Dhungana, Hiramani, et al.
Publicado: (2013)

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo
por: Keuters, Meike Hedwig, et al.
Publicado: (2021)

Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy
por: Huuskonen, Mikko T., et al.
Publicado: (2016)

Gender-Specific Mechanism of Synaptic Impairment and Its Prevention by GCSF in a Mouse Model of ALS
por: Naumenko, Nikolay, et al.
Publicado: (2011)

Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease
por: Magga, Johanna, et al.
Publicado: (2010)

Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment
por: Savchenko, Ekaterina, et al.
Publicado: (2016)

The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis
por: Pollari, Eveliina, et al.
Publicado: (2014)

Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications
por: Malm, Tarja, et al.
Publicado: (2011)

Glycogen Synthase Kinase-3β: A Mediator of Inflammation in Alzheimer's Disease?
por: Koistinaho, Jari, et al.
Publicado: (2011)

Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway
por: Kanninen, Katja, et al.
Publicado: (2011)

A brain cytokine-independent switch in cortical activity marks the onset of sickness behavior triggered by acute peripheral inflammation
por: Kurki, Samu N., et al.
Publicado: (2023)

NF‐E2‐related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin‐1 mutated Alzheimer's disease astrocytes
por: Oksanen, Minna, et al.
Publicado: (2019)

SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase
por: Kettunen, Pinja, et al.
Publicado: (2023)

Dysfunction of Cellular Proteostasis in Parkinson’s Disease
por: Lehtonen, Šárka, et al.
Publicado: (2019)

Mechanisms of mutant SOD1 induced mitochondrial toxicity in amyotrophic lateral sclerosis
por: Vehviläinen, Piia, et al.
Publicado: (2014)

Proteostasis Disturbances and Inflammation in Neurodegenerative Diseases
por: Sonninen, Tuuli-Maria, et al.
Publicado: (2020)

Blood–Brain Barrier and Neurodegenerative Diseases—Modeling with iPSC-Derived Brain Cells
por: Wu, Ying-Chieh, et al.
Publicado: (2021)

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
por: Liddell, Jeffrey R., et al.
Publicado: (2016)

Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease
por: Puli, Lakshman, et al.
Publicado: (2012)

Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms
por: Oksanen, Minna, et al.
Publicado: (2019)

CNS Redox Homeostasis and Dysfunction in Neurodegenerative Diseases
por: Goldsteins, Gundars, et al.
Publicado: (2022)

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
por: Jäntti, Henna, et al.
Publicado: (2022)

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling
por: Koivumäki, Jussi T., et al.
Publicado: (2018)

Retinal Degeneration In A Mouse Model Of CLN5 Disease Is Associated With Compromised Autophagy
por: Leinonen, Henri, et al.
Publicado: (2017)

Lack of collagen XV is protective after ischemic stroke in mice
por: Dhungana, Hiramani, et al.
Publicado: (2017)

Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids
por: Fagerlund, Ilkka, et al.
Publicado: (2021)

Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke
por: Kolosowska, Natalia, et al.
Publicado: (2019)

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice
por: Puris, Elena, et al.
Publicado: (2021)

Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation
por: Dhungana, Hiramani, et al.
Publicado: (2017)

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer’s Disease
por: Gynther, Mikko, et al.
Publicado: (2022)

Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder
por: Savchenko, Ekaterina, et al.
Publicado: (2017)

ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase
por: Jaronen, Merja, et al.
Publicado: (2014)

Perineuronal nets in neurodegeneration
por: Lemarchant, Sighild, et al.
Publicado: (2016)

Activation of P2X7 Receptors in Peritoneal and Meningeal Mast Cells Detected by Uptake of Organic Dyes: Possible Purinergic Triggers of Neuroinflammation in Meninges
por: Nurkhametova, Dilyara, et al.
Publicado: (2019)

Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation
por: Byts, Nadiya, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rl29u8tkkfm39sqe0ijaidilqd