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Cardiomyocyte death induced by ischaemic/hypoxic stress is differentially affected by distinct purinergic P2 receptors

Blood levels of extracellular nucleotides (e.g. ATP) are greatly increased during heart ischaemia, but, despite the presence of their specific receptors on cardiomyocytes (both P2X and P2Y subtypes), their effects on the subsequent myocardial damage are still unknown. In this study, we aimed at inve...

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Detalles Bibliográficos
Autores principales: Cosentino, Simona, Banfi, Cristina, Burbiel, Joachim C, Luo, Haijian, Tremoli, Elena, Abbracchio, Maria P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365886/
https://www.ncbi.nlm.nih.gov/pubmed/21762374
http://dx.doi.org/10.1111/j.1582-4934.2011.01382.x