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Overexpression of the human ZNF300 gene enhances growth and metastasis of cancer cells through activating NF-kB pathway

Zinc finger proteins (ZNF) play important roles in various physiological processes. Here we report that ZNF300, a novel zinc finger protein, identified specifically in humans, promotes tumour development by modulating the NF-κB pathway. Inflammatory factors were found to induce ZNF300 expression in...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Wang, Xian-guo, Xu, Jun-hua, Wu, Xiang-Peng, Qiu, Hong-ling, Yi, Hong, Li, Wen-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365892/
https://www.ncbi.nlm.nih.gov/pubmed/21777376
http://dx.doi.org/10.1111/j.1582-4934.2011.01388.x