Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells

Plumbagin (PLB) has been shown to have anticancer activities in animal models, but the role of PLB in prostate cancer treatment is unclear. This study aimed to investigate the effects of PLB on apoptosis and autophagy and the underlying mechanisms in human prostate cancer cell lines PC-3 and DU145....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Zhi-Wei, Li, Xing-Xiao, He, Zhi-Xu, Pan, Shu-Ting, Yang, Yinxue, Zhang, Xueji, Chow, Kevin, Yang, Tianxin, Qiu, Jia-Xuan, Zhou, Qingyu, Tan, Jun, Wang, Dong, Zhou, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366042/
https://www.ncbi.nlm.nih.gov/pubmed/25834399
http://dx.doi.org/10.2147/DDDT.S75976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366042/
https://www.ncbi.nlm.nih.gov/pubmed/25834399
http://dx.doi.org/10.2147/DDDT.S75976

Ejemplares similares