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Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein

Aggregation of α-synuclein (α-syn) is associated with the development of a number of neurodegenerative diseases, including Parkinson’s disease (PD). The formation of α-syn aggregates results from aberrant accumulation of misfolded α-syn and insufficient or impaired activity of the two main intracell...

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Detalles Bibliográficos
Autores principales:	Kilpatrick, Kiri, Zeng, Yimeng, Hancock, Tommy, Segatori, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366176/ https://www.ncbi.nlm.nih.gov/pubmed/25790376 http://dx.doi.org/10.1371/journal.pone.0120819

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