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Association of TLR5 Gene Polymorphisms in Ulcerative Colitis Patients of North India and Their Role in Cytokine Homeostasis

BACKGROUND AND AIM: In health, TLR signaling protects the intestinal epithelial barrier and in disease, aberrant TLR signaling stimulates diverse inflammatory responses. Association of TLR polymorphisms is ethnicity dependent but how they impact the complex pathogenesis of IBD is not clearly defined...

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Detalles Bibliográficos
Autores principales: Meena, Naresh Kumar, Ahuja, Vineet, Meena, Kusumlata, Paul, Jaishree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366177/
https://www.ncbi.nlm.nih.gov/pubmed/25789623
http://dx.doi.org/10.1371/journal.pone.0120697