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In Vivo Regulation of Erythropoiesis by Chemically Inducible Dimerization of the Erythropoietin Receptor Intracellular Domain

Erythropoietin (Epo) and its receptor (EpoR) are required for the regulation of erythropoiesis. Epo binds to the EpoR homodimer on the surface of erythroid progenitors and erythroblasts, and positions the intracellular domains of the homodimer to be in close proximity with each other. This conformat...

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Detalles Bibliográficos
Autores principales: Suzuki, Norio, Mukai, Harumi Y., Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366189/
https://www.ncbi.nlm.nih.gov/pubmed/25790231
http://dx.doi.org/10.1371/journal.pone.0119442