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Nuclear Envelope Protein Lem2 is Required for Mouse Development and Regulates MAP and AKT Kinases

The nuclear lamina, along with associated nuclear membrane proteins, is a nexus for regulating signaling in the nucleus. Numerous human diseases arise from mutations in lamina proteins, and experimental models for these disorders have revealed aberrant regulation of various signaling pathways. Previ...

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Detalles Bibliográficos
Autores principales: Tapia, Olga, Fong, Loren G., Huber, Michael D., Young, Stephen G., Gerace, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366207/
https://www.ncbi.nlm.nih.gov/pubmed/25790465
http://dx.doi.org/10.1371/journal.pone.0116196