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Liver Inflammation and Metabolic Signaling in Apc(Min/+) Mice: The Role of Cachexia Progression

The Apc(Min/+) mouse exhibits an intestinal tumor associated loss of muscle and fat that is accompanied by chronic inflammation, insulin resistance and hyperlipidemia. Since the liver governs systemic energy demands through regulation of glucose and lipid metabolism, it is likely that the liver is a...

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Detalles Bibliográficos
Autores principales: Narsale, Aditi A., Enos, Reilly T., Puppa, Melissa J., Chatterjee, Saurabh, Murphy, E. Angela, Fayad, Raja, Pena, Majorette O’, Durstine, J. Larry, Carson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366213/
https://www.ncbi.nlm.nih.gov/pubmed/25789991
http://dx.doi.org/10.1371/journal.pone.0119888