Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability

Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...

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Detalles Bibliográficos
Autores principales: Herrero, Ana B., San Miguel, Jesús, Gutierrez, Norma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366222/
https://www.ncbi.nlm.nih.gov/pubmed/25790254
http://dx.doi.org/10.1371/journal.pone.0121581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366222/
https://www.ncbi.nlm.nih.gov/pubmed/25790254
http://dx.doi.org/10.1371/journal.pone.0121581

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