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Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability
Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366222/ https://www.ncbi.nlm.nih.gov/pubmed/25790254 http://dx.doi.org/10.1371/journal.pone.0121581 |