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Pleiotropic and Sex-Specific Effects of Cancer GWAS SNPs on Melanoma Risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study

BACKGROUND: Several regions of the genome show pleiotropic associations with multiple cancers. We sought to evaluate whether 181 single-nucleotide polymorphisms previously associated with various cancers in genome-wide association studies were also associated with melanoma risk. METHODS: We evaluate...

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Detalles Bibliográficos
Autores principales: Kocarnik, Jonathan M., Park, S. Lani, Han, Jiali, Dumitrescu, Logan, Cheng, Iona, Wilkens, Lynne R., Schumacher, Fredrick R., Kolonel, Laurence, Carlson, Chris S., Crawford, Dana C., Goodloe, Robert J., Dilks, Holli H., Baker, Paxton, Richardson, Danielle, Matise, Tara C., Ambite, José Luis, Song, Fengju, Qureshi, Abrar A., Zhang, Mingfeng, Duggan, David, Hutter, Carolyn, Hindorff, Lucia, Bush, William S., Kooperberg, Charles, Le Marchand, Loic, Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366224/
https://www.ncbi.nlm.nih.gov/pubmed/25789475
http://dx.doi.org/10.1371/journal.pone.0120491