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Pleiotropic and Sex-Specific Effects of Cancer GWAS SNPs on Melanoma Risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study
BACKGROUND: Several regions of the genome show pleiotropic associations with multiple cancers. We sought to evaluate whether 181 single-nucleotide polymorphisms previously associated with various cancers in genome-wide association studies were also associated with melanoma risk. METHODS: We evaluate...
Autores principales: | Kocarnik, Jonathan M., Park, S. Lani, Han, Jiali, Dumitrescu, Logan, Cheng, Iona, Wilkens, Lynne R., Schumacher, Fredrick R., Kolonel, Laurence, Carlson, Chris S., Crawford, Dana C., Goodloe, Robert J., Dilks, Holli H., Baker, Paxton, Richardson, Danielle, Matise, Tara C., Ambite, José Luis, Song, Fengju, Qureshi, Abrar A., Zhang, Mingfeng, Duggan, David, Hutter, Carolyn, Hindorff, Lucia, Bush, William S., Kooperberg, Charles, Le Marchand, Loic, Peters, Ulrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366224/ https://www.ncbi.nlm.nih.gov/pubmed/25789475 http://dx.doi.org/10.1371/journal.pone.0120491 |
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