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Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study

Heart failure (HF) is accompanied by complex alterations in myocardial energy metabolism. Up to 40% of HF patients have dyssynchronous ventricular contraction, which is an independent indicator of mortality. We hypothesized that electromechanical dyssynchrony significantly affects metabolic remodeli...

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Detalles Bibliográficos
Autores principales: Shibayama, Junko, Yuzyuk, Tatiana N., Cox, James, Makaju, Aman, Miller, Mickey, Lichter, Justin, Li, Hui, Leavy, Jane D., Franklin, Sarah, Zaitsev, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366225/
https://www.ncbi.nlm.nih.gov/pubmed/25790351
http://dx.doi.org/10.1371/journal.pone.0118974