Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria

In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyond. These proteins include numerous bacterial virulence factors. Thus, bacterial enzymes that promote disulfide bond formation represent targets for compounds inhibiting bacterial virulence. Here, we...

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Detalles Bibliográficos
Autores principales: Landeta, Cristina, Blazyk, Jessica L., Hatahet, Feras, Meehan, Brian M., Eser, Markus, Myrick, Alissa, Bronstain, Ludmila, Minami, Shoko, Arnold, Holly, Ke, Na, Rubin, Eric J., Furie, Barbara C., Furie, Bruce, Beckwith, Jon, Dutton, Rachel, Boyd, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366281/
https://www.ncbi.nlm.nih.gov/pubmed/25686372
http://dx.doi.org/10.1038/nchembio.1752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366281/
https://www.ncbi.nlm.nih.gov/pubmed/25686372
http://dx.doi.org/10.1038/nchembio.1752

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