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Assessment of Cancer Cell Line Representativeness using Microarrays for Merkel Cell Carcinoma

When using cell lines to study cancer, phenotypic similarity to the original tumor is paramount. Yet, little has been done to characterize how closely Merkel cell carcinoma (MCC) cell lines model native tumors. To determine their similarity to MCC tumor samples, we characterized MCC cell lines via g...

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Detalles Bibliográficos
Autores principales: Daily, Kenneth, Coxon, Amy, Williams, Jonathan S., Lee, Chyi-Chia Richard, Coit, Daniel G., Busam, Klaus J., Brownell, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366303/
https://www.ncbi.nlm.nih.gov/pubmed/25521454
http://dx.doi.org/10.1038/jid.2014.518