Caspase-Mediated Apoptosis in the Cochleae Contributes to the Early Onset of Hearing Loss in A/J Mice

A/J and C57BL/6 J (B6) mice share a mutation in Cdh23 (ahl allele) and are characterized by age-related hearing loss. However, hearing loss occurs much earlier in A/J mice at about four weeks of age. Recent study has revealed that a mutation in citrate synthase (Cs) is one of the main contributors,...

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Detalles Bibliográficos
Autores principales: Han, Xu, Ge, Ruli, Xie, Gang, Li, Ping, Zhao, Xin, Gao, Lixiang, Zhang, Heng, Wang, Oumei, Huang, Fei, Han, Fengchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366423/
https://www.ncbi.nlm.nih.gov/pubmed/25732708
http://dx.doi.org/10.1177/1759091415573985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366423/
https://www.ncbi.nlm.nih.gov/pubmed/25732708
http://dx.doi.org/10.1177/1759091415573985

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