Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1

The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain, including progenitor division and neuronal migration. Here we show that Cenpj, also known as CPAP, a microcephaly gene, is a transcriptional target of Ascl1 in the embryonic cerebral cortex. We have characteri...

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Detalles Bibliográficos
Autores principales: Garcez, Patricia P., Diaz-Alonso, Javier, Crespo-Enriquez, Ivan, Castro, Diogo, Bell, Donald, Guillemot, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366522/
https://www.ncbi.nlm.nih.gov/pubmed/25753651
http://dx.doi.org/10.1038/ncomms7474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366522/
https://www.ncbi.nlm.nih.gov/pubmed/25753651
http://dx.doi.org/10.1038/ncomms7474

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