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Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1
The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain, including progenitor division and neuronal migration. Here we show that Cenpj, also known as CPAP, a microcephaly gene, is a transcriptional target of Ascl1 in the embryonic cerebral cortex. We have characteri...
Autores principales: | Garcez, Patricia P., Diaz-Alonso, Javier, Crespo-Enriquez, Ivan, Castro, Diogo, Bell, Donald, Guillemot, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366522/ https://www.ncbi.nlm.nih.gov/pubmed/25753651 http://dx.doi.org/10.1038/ncomms7474 |
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