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Biased Signaling in Naturally Occurring Mutations in Human Melanocortin-3 Receptor Gene

The melanocortin-3 receptor (MC3R) is primarily expressed in the hypothalamus and plays an important role in the regulation of energy homeostasis. Recently, some studies demonstrated that MC3R also signals through mitogen-activated protein kinases (MAPKs), especially extracellular signal-regulated k...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Huang, Hui, Tao, Ya-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366641/
https://www.ncbi.nlm.nih.gov/pubmed/25798062
http://dx.doi.org/10.7150/ijbs.11032