Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening

Synaptotagmin 1 (Syt1), a major Ca(2+) sensor in neuroexocytosis, utilizes SNARE- and membrane-binding to regulate vesicle fusion, a required process for neurotransmitter release at the synapse. However, the mechanism by which Syt1 orchestrates SNARE- and membrane- binding to control individual vesi...

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Detalles Bibliográficos
Autores principales: Lai, Ying, Lou, Xiaochu, Diao, Jiajie, Shin, Yeon-Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366854/
https://www.ncbi.nlm.nih.gov/pubmed/25791821
http://dx.doi.org/10.1038/srep09267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366854/
https://www.ncbi.nlm.nih.gov/pubmed/25791821
http://dx.doi.org/10.1038/srep09267

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