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hERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma

BACKGROUND: hERG1 channels are aberrantly expressed in human cancers. The expression, functional role and clinical significance of hERG1 channels in pancreatic ductal adenocarcinoma (PDAC) is lacking. METHODS: hERG1 expression was tested in PDAC primary samples assembled as tissue microarray by immu...

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Detalles Bibliográficos
Autores principales: Lastraioli, E, Perrone, G, Sette, A, Fiore, A, Crociani, O, Manoli, S, D'Amico, M, Masselli, M, Iorio, J, Callea, M, Borzomati, D, Nappo, G, Bartolozzi, F, Santini, D, Bencini, L, Farsi, M, Boni, L, Di Costanzo, F, Schwab, A, Onetti Muda, A, Coppola, R, Arcangeli, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366888/
https://www.ncbi.nlm.nih.gov/pubmed/25719829
http://dx.doi.org/10.1038/bjc.2015.28