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β-irradiation ((166)Ho patch)-induced skin injury in mini-pigs: effects on NF-κB and COX-2 expression in the skin

In the present study, the detrimental effect of β-emission on pig skin was evaluated. Skin injury was modeled in mini-pigs by exposing the animals to 50 and 100 Gy of β-emission delivered by (166)Ho patches. Clinicopathological and immunohistochemical changes in exposed skin were monitored for 18 we...

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Detalles Bibliográficos
Autores principales: Kim, Joong-Sun, Rhim, Kyung-Jin, Jang, Won-Seok, Lee, Sun-Joo, Son, Yeonghoon, Lee, Seung-Sook, Park, Sunhoo, Lim, Sang Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367138/
https://www.ncbi.nlm.nih.gov/pubmed/24962420
http://dx.doi.org/10.4142/jvs.2015.16.1.1