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Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD

Psychostimulants show therapeutic efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD). It is generally assumed that they ameliorate ADHD symptoms via interfering with monoaminergic signaling. We combined behavioral pharmacology, neurochemistry and molecular analyses to ident...

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Detalles Bibliográficos
Autores principales: Yen, Yi-Chun, Gassen, Nils C., Zellner, Andreas, Rein, Theo, Landgraf, Rainer, Wotjak, Carsten T., Anderzhanova, Elmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367184/
https://www.ncbi.nlm.nih.gov/pubmed/25852508
http://dx.doi.org/10.3389/fnbeh.2015.00067