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Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD
Psychostimulants show therapeutic efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD). It is generally assumed that they ameliorate ADHD symptoms via interfering with monoaminergic signaling. We combined behavioral pharmacology, neurochemistry and molecular analyses to ident...
Autores principales: | Yen, Yi-Chun, Gassen, Nils C., Zellner, Andreas, Rein, Theo, Landgraf, Rainer, Wotjak, Carsten T., Anderzhanova, Elmira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367184/ https://www.ncbi.nlm.nih.gov/pubmed/25852508 http://dx.doi.org/10.3389/fnbeh.2015.00067 |
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