Comparisons with Amyloid-β Reveal an Aspartate Residue That Stabilizes Fibrils of the Aortic Amyloid Peptide Medin

Aortic medial amyloid (AMA) is the most common localized human amyloid, occurring in virtually all of the Caucasian population over the age of 50. The main protein component of AMA, medin, readily assembles into amyloid-like fibrils in vitro. Despite the prevalence of AMA, little is known about the...

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Detalles Bibliográficos
Autores principales: Davies, Hannah A., Madine, Jillian, Middleton, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367279/
https://www.ncbi.nlm.nih.gov/pubmed/25614623
http://dx.doi.org/10.1074/jbc.M114.602177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367279/
https://www.ncbi.nlm.nih.gov/pubmed/25614623
http://dx.doi.org/10.1074/jbc.M114.602177

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