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Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Detalles Bibliográficos
Autores principales: Adeniran, Ismail, MacIver, David H., Hancox, Jules C., Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367530/
https://www.ncbi.nlm.nih.gov/pubmed/25852567
http://dx.doi.org/10.3389/fphys.2015.00078