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Systematic exploration of autonomous modules in noisy microRNA-target networks for testing the generality of the ceRNA hypothesis

BACKGROUND: In the competing endogenous RNA (ceRNA) hypothesis, different transcripts communicate through a competition for their common targeting microRNAs (miRNAs). Individual examples have clearly shown the functional importance of ceRNA in gene regulation and cancer biology. It remains unclear t...

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Detalles Bibliográficos
Autores principales: Yip, Danny Kit-Sang, Pang, Iris K, Yip, Kevin Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367885/
https://www.ncbi.nlm.nih.gov/pubmed/25539629
http://dx.doi.org/10.1186/1471-2164-15-1178