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Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in mice

BACKGROUND: Silent information regulator 2 related enzyme 1 (SIRT1) is one of the key factors in the mechanism of calorie restriction (CR) extending lifespan of animals. The aim of the study is to investigate if CR prolongs ovarian lifespan in mice through activating SIRT1 signaling. METHODS: In the...

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Detalles Bibliográficos
Autores principales: Liu, Wei-Juan, Zhang, Xing-Mei, Wang, Na, Zhou, Xiao-Ling, Fu, Yu-Cai, Luo, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367909/
https://www.ncbi.nlm.nih.gov/pubmed/25889584
http://dx.doi.org/10.1186/s40001-015-0114-8