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Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in mice
BACKGROUND: Silent information regulator 2 related enzyme 1 (SIRT1) is one of the key factors in the mechanism of calorie restriction (CR) extending lifespan of animals. The aim of the study is to investigate if CR prolongs ovarian lifespan in mice through activating SIRT1 signaling. METHODS: In the...
Autores principales: | Liu, Wei-Juan, Zhang, Xing-Mei, Wang, Na, Zhou, Xiao-Ling, Fu, Yu-Cai, Luo, Li-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367909/ https://www.ncbi.nlm.nih.gov/pubmed/25889584 http://dx.doi.org/10.1186/s40001-015-0114-8 |
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