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Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

The purpose of this study was to develop a novel lipid–polymer hybrid drug carrier comprised of folate (FA) modified lipid-shell and polymer-core nanoparticles (FLPNPs) for sustained, controlled, and targeted delivery of paclitaxel (PTX). The core-shell NPs consist of 1) a poly(ε-caprolactone) hydro...

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Detalles Bibliográficos
Autores principales: Zhang, Linhua, Zhu, Dunwan, Dong, Xia, Sun, Hongfan, Song, Cunxian, Wang, Chun, Kong, Deling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368035/
https://www.ncbi.nlm.nih.gov/pubmed/25844039
http://dx.doi.org/10.2147/IJN.S77667