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N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters

BACKGROUND: Glycosylation, i.e the enzymatic addition of oligosaccharides (or glycans) to proteins and lipids, known as glycosylation, is one of the most common co-/posttranslational modifications of proteins. Many important biological roles of glycoproteins are modulated by N-linked oligosaccharide...

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Detalles Bibliográficos
Autores principales: Testa, Roberto, Vanhooren, Valerie, Bonfigli, Anna Rita, Boemi, Massimo, Olivieri, Fabiola, Ceriello, Antonio, Genovese, Stefano, Spazzafumo, Liana, Borelli, Vincenzo, Bacalini, Maria Giulia, Salvioli, Stefano, Garagnani, Paolo, Dewaele, Sylviane, Libert, Claude, Franceschi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368037/
https://www.ncbi.nlm.nih.gov/pubmed/25793407
http://dx.doi.org/10.1371/journal.pone.0119983