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Enhanced specific antitumor immunity of dendritic cells transduced with the glypican 3 gene and co-cultured with cytokine-induced killer cells against hepatocellular carcinoma cells

Dendritic cell (DC)-based cancer immunotherapy requires an immunogenic tumor-associated antigen and an effective therapeutic strategy. Glypican 3 (GPC3) is a valuable diagnostic marker and a potential therapeutic target in hepatocellular carcinoma (HCC). The present study investigated whether DCs tr...

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Detalles Bibliográficos
Autores principales: WANG, YULIANG, WANG, YINLONG, MU, HONG, LIU, TAO, CHEN, XIAOBO, SHEN, ZHONGYANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368068/
https://www.ncbi.nlm.nih.gov/pubmed/25625609
http://dx.doi.org/10.3892/mmr.2015.3239