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Genetic Variants in MiRNA Processing Genes and Pre-MiRNAs Are Associated with the Risk of Chronic Lymphocytic Leukemia

Genome wide association studies (GWAS) have identified several low-penetrance susceptibility alleles in chronic lymphocytic leukemia (CLL). Nevertheless, these studies scarcely study regions that are implicated in non-coding molecules such as microRNAs (miRNAs). Abnormalities in miRNAs, as altered e...

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Detalles Bibliográficos
Autores principales: Martin-Guerrero, Idoia, Gutierrez-Camino, Angela, Lopez-Lopez, Elixabet, Bilbao-Aldaiturriaga, Nerea, Pombar-Gomez, Maria, Ardanaz, Maite, Garcia-Orad, Africa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368096/
https://www.ncbi.nlm.nih.gov/pubmed/25793711
http://dx.doi.org/10.1371/journal.pone.0118905