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Immunotherapeutic intervention with oncolytic adenovirus in mouse mammary tumors

The goal is to elucidate the immune modulating activity of an adenovirus (Adv) vector which showed therapeutic activity in human clinical trials. The oncolytic adenovirus (Adv/CD-TK) expressing two suicide genes was tested in two HER2/neu positive BALB/c mouse mammary tumor systems: rat neu-induced...

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Detalles Bibliográficos
Autores principales: Gibson, Heather, Munns, Stephanie, Freytag, Svend, Barton, Kenneth, Veenstra, Jesse, Bettahi, Ilham, Bissonette, Jayne, Wei, Wei-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368120/
https://www.ncbi.nlm.nih.gov/pubmed/25949865
http://dx.doi.org/10.4161/2162402X.2014.984523