Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults

Antigen-specific multifunctional T cells that secrete interferon-γ, interleukin-2 and tumour necrosis factor-α simultaneously after activation are important for the control of many infections. It is unclear if these CD8(+) T cells are at an early or late stage of differentiation and whether telomere...

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Detalles Bibliográficos
Autores principales: Riddell, Natalie E, Griffiths, Stephen J, Rivino, Laura, King, David C B, Teo, Guo H, Henson, Sian M, Cantisan, Sara, Solana, Rafael, Kemeny, David M, MacAry, Paul A, Larbi, Anis, Akbar, Arne N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368162/
https://www.ncbi.nlm.nih.gov/pubmed/25314332
http://dx.doi.org/10.1111/imm.12409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368162/
https://www.ncbi.nlm.nih.gov/pubmed/25314332
http://dx.doi.org/10.1111/imm.12409

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