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Triclabendazole Sulfoxide Causes Stage-Dependent Embryolethality in Zebrafish and Mouse In Vitro

BACKGROUND: Fascioliasis and paragonimiasis are widespread foodborne trematode diseases, affecting millions of people in more than 75 countries. The treatment of choice for these parasitic diseases is based on triclabendazole, a benzimidazole derivative which has been suggested as a promising drug t...

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Detalles Bibliográficos
Autores principales: Boix, Nuria, Teixido, Elisabet, Vila-Cejudo, Marta, Ortiz, Pedro, Ibáñez, Elena, Llobet, Juan M., Barenys, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368200/
https://www.ncbi.nlm.nih.gov/pubmed/25793498
http://dx.doi.org/10.1371/journal.pone.0121308