Spatio-temporal Model of Endogenous ROS and Raft-Dependent WNT/Beta-Catenin Signaling Driving Cell Fate Commitment in Human Neural Progenitor Cells

Canonical WNT/β-catenin signaling is a central pathway in embryonic development, but it is also connected to a number of cancers and developmental disorders. Here we apply a combined in-vitro and in-silico approach to investigate the spatio-temporal regulation of WNT/β-catenin signaling during the e...

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Detalles Bibliográficos
Autores principales: Haack, Fiete, Lemcke, Heiko, Ewald, Roland, Rharass, Tareck, Uhrmacher, Adelinde M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368204/
https://www.ncbi.nlm.nih.gov/pubmed/25793621
http://dx.doi.org/10.1371/journal.pcbi.1004106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368204/
https://www.ncbi.nlm.nih.gov/pubmed/25793621
http://dx.doi.org/10.1371/journal.pcbi.1004106

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