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Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring

Glutamate receptors for N-methyl-d-aspartate (NMDA) are involved in early brain development. The kynurenine pathway of tryptophan metabolism includes the NMDA receptor agonist quinolinic acid and the antagonist kynurenic acid. We now report that prenatal inhibition of the pathway in rats with 3,4-di...

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Detalles Bibliográficos
Autores principales: Khalil, Omari S, Pisar, Mazura, Forrest, Caroline M, Vincenten, Maria C J, Darlington, L Gail, Stone, Trevor W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368408/
https://www.ncbi.nlm.nih.gov/pubmed/24646396
http://dx.doi.org/10.1111/ejn.12535