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Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring
Glutamate receptors for N-methyl-d-aspartate (NMDA) are involved in early brain development. The kynurenine pathway of tryptophan metabolism includes the NMDA receptor agonist quinolinic acid and the antagonist kynurenic acid. We now report that prenatal inhibition of the pathway in rats with 3,4-di...
Autores principales: | Khalil, Omari S, Pisar, Mazura, Forrest, Caroline M, Vincenten, Maria C J, Darlington, L Gail, Stone, Trevor W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368408/ https://www.ncbi.nlm.nih.gov/pubmed/24646396 http://dx.doi.org/10.1111/ejn.12535 |
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